Recombinant Human CIRBP Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1272
Recombinant Human CIRBP Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1272
Catalog No.: BLPSN-1272
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | Q14011 |
| Synonym | CIRP |
| Background | CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator.CIRBP can bind the 3 translated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly. |
| Description | A DNA sequence encoding the human CIRBP (Q14011) (Met1-Glu172) was expressed with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | His |
| AA Sequence | Met1-Glu172 |
| Molecular Weight | The recombinant human CIRBP consists of 187 a.a. and predicts a molecular mass of 20.5 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile 20mM Tris, 500mM NaCl, 0.25M Imi, 20% glycerol.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
