Recombinant Human CIRBP Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1272
Recombinant Human CIRBP Protein (His Tag)

Recombinant Human CIRBP Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1272
Catalog No.: BLPSN-1272

Product Overview

Tag His
Host Species Human
Accession Q14011
Synonym CIRP
Background CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator.CIRBP can bind the 3 translated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.
Description A DNA sequence encoding the human CIRBP (Q14011) (Met1-Glu172) was expressed with a His tag at the N-terminus.
Source E.coli
Predicted N Terminal His
AA Sequence Met1-Glu172
Molecular Weight The recombinant human CIRBP consists of 187 a.a. and predicts a molecular mass of 20.5 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions.
Purity >90% as determined by SDS-PAGE
Endotoxin Please contact us for more information.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile 20mM Tris, 500mM NaCl, 0.25M Imi, 20% glycerol..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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