Recombinant Human CHRNB3 Protein (ECD, His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1261
Recombinant Human CHRNB3 Protein (ECD, His Tag)

Recombinant Human CHRNB3 Protein (ECD, His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1261
Catalog No.: BLPSN-1261

Product Overview

Tag His
Host Species Human
Accession NP_000740.1
Background Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence.
Description A DNA sequence encoding the human CHRNB3 (NP_000740.1) (Met1-Leu232) was expressed with a His tag at the C-terminus.
Source HEK293
Predicted N Terminal Ile 25
AA Sequence Met1-Leu232
Molecular Weight The recombinant human CHRNB3 consists 219 a.a. and predicts a molecular mass of 25.7 kDa.
Purity >90% as determined by SDS-PAGE.
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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