Recombinant Human CHRNA5 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1259
Recombinant Human CHRNA5 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1259
Collections: Other recombinant proteins, Recombinant proteins
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NP_000736.2 |
| Synonym | LNCR2 |
| Background | Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer. CHRNA5 may influence susceptibility to lung cancer among Han smokers. Genetic variation in nicotinic receptor alpha 5 (CHRNA5) has been associated with increased risk of addiction-associated phenotypes in humans. |
| Description | A DNA sequence encoding the human CHRNA5 (NP_000736.2) (Met1-Thr254) was expressed with a His tag at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Arg 23 |
| AA Sequence | Met1-Thr254 |
| Molecular Weight | The recombinant human CHRNA5 consists 243 a.a. and predicts a molecular mass of 28 kDa. |
| Purity | >90% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
