Recombinant Human CEP57 Protein (GST Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1220
Recombinant Human CEP57 Protein (GST Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1220
Catalog No.: BLPSN-1220
Product Overview
| Tag | GST |
| Host Species | Human |
| Accession | Q86XR8 |
| Synonym | MVA2, PIG8, TSP57 |
| Background | CEP57 is a centrosomal protein and is involved in nucleating and stabilizing microtubules. CEP57 was initially identified as a regulator of centriole overduplication in an RNA interference screen. There is a link between altered microenvironmental signaling cues such as FGF-2 overexpression and mitotic instability and provide a rationale for the therapeutic targeting of the FGF-2/FGFR1/CEP57 axis in prostate cancer. CEP57 is involved in intracellular transport processes, and its overexpression causes mitotic defects as well as abnormal microtubule nucleation and bundling. |
| Description | A DNA sequence encoding the human CEP57 (Q86XR8-1) (Ser118-Arg226) was expressed with the GST tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | Met |
| AA Sequence | Ser118-Arg226 |
| Molecular Weight | The recombinant human CEP57/GST chimera consists of 343 a.a. and has a predicted molecular mass of 40.3 kDa. It migrates as an approximately 35-43 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
