Recombinant Human Calnexin Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-0524
Recombinant Human Calnexin Protein (Fc Tag)

Recombinant Human Calnexin Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-0524
Catalog No.: BLPSN-0524

Product Overview

Tag Fc
Host Species Human
Accession P27824
Synonym CNX, IP90, P90
Background Calnexin is a calcium-binding protein that belongs to the calreticulin family. It interacts with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
Description A DNA sequence encoding the human CANX (P27824) (Met1-Pro481) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Source HEK293
Predicted N Terminal His 21
AA Sequence Met1-Pro481
Molecular Weight The recombinant human CANX/Fc is a disulfide-linked homodimer. The reduced monomer comprises 702 a.a. and has a predicted molecular mass of 79.4 kDa. The apparent molecular mass of the protein is approximately 110 kDa in SDS-PAGE under reducing conditions.
Purity >85% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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