Recombinant Human Calnexin Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0524
Recombinant Human Calnexin Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0524
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | Fc |
Host Species | Human |
Accession | P27824 |
Synonym | CNX, IP90, P90 |
Background | Calnexin is a calcium-binding protein that belongs to the calreticulin family. It interacts with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. |
Description | A DNA sequence encoding the human CANX (P27824) (Met1-Pro481) was expressed, fused with the Fc region of human IgG1 at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | His 21 |
AA Sequence | Met1-Pro481 |
Molecular Weight | The recombinant human CANX/Fc is a disulfide-linked homodimer. The reduced monomer comprises 702 a.a. and has a predicted molecular mass of 79.4 kDa. The apparent molecular mass of the protein is approximately 110 kDa in SDS-PAGE under reducing conditions. |
Purity | >85% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |