Recombinant Human Calnexin Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0524

Recombinant Human Calnexin Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0524
Catalog No.: BLPSN-0524
Product Overview
Tag | Fc |
Host Species | Human |
Accession | P27824 |
Synonym | CNX, IP90, P90 |
Background | Calnexin is a calcium-binding protein that belongs to the calreticulin family. It interacts with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. |
Description | A DNA sequence encoding the human CANX (P27824) (Met1-Pro481) was expressed, fused with the Fc region of human IgG1 at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | His 21 |
AA Sequence | Met1-Pro481 |
Molecular Weight | The recombinant human CANX/Fc is a disulfide-linked homodimer. The reduced monomer comprises 702 a.a. and has a predicted molecular mass of 79.4 kDa. The apparent molecular mass of the protein is approximately 110 kDa in SDS-PAGE under reducing conditions. |
Purity | >85% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |