Recombinant Human BPIFA2 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0449
Recombinant Human BPIFA2 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0449
Collections: Other recombinant proteins, Recombinant proteins
Product Overview
| Tag | Fc |
| Host Species | Human |
| Accession | Q96DR5 |
| Synonym | bA49G10.1, C20orf70, PSP, SPLUNC2 |
| Background | C2orf7 belongs to the BPI/LBP/Plunc superfamily, Plunc family. PLUNC family is comprised by mucosal secretory proteins that are predicted to be structurally similar to lipid-binding and host-defense proteins including bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein. C2orf7 can be detected in submandibular gland. C2orf7 gene contains 9 distinct gt-ag introns. Transcription produces 6 different mRNAs, 4 alternatively spliced variants and 2 unspliced forms. There are 2 probable alternative promotors, 3 non overlapping alternative last exons and 4 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 3' end. 8 bp of this gene are antisense to spliced gene glopa, raising the possibility of regulated alternate expression. C2orf7 is expected to have molecular function (lipid binding) and to localize in extracellular region. It is a salivary protein of unknown function. |
| Description | A DNA sequence encoding the human C20orf70 (Q96DR5) (Met1-Ile249) was expressed, fused with the Fc region of human IgG1 at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Glu 19 |
| AA Sequence | Met1-Ile249 |
| Molecular Weight | The recombinant human C20orf70/Fc is a disulfide-linked homodimer. The reduced monomer comprises 470 a.a. and has a predicted molecular mass of 51.8 kDa. The apparent molecular mass of the protein is approximately 59 kDa in SDS-PAGE under reducing conditions. |
| Purity | >94% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
