Recombinant Human BEX1 Protein

Beta LifeScience SKU/CAT #: BL-3668PS
Recombinant Human BEX1 Protein

Recombinant Human BEX1 Protein

Beta LifeScience SKU/CAT #: BL-3668PS
Catalog No.: BL-3668PS

Product Overview

Tag N/A
Host Species Human
Synonym BEX2, HBEX2, HGR74-h, Protein BEX1, Brain-expressed X-linked protein 1.
Background Brain Expressed X-Linked 1 (BEX1) which participates in cell cycle progression and neuronal differentiation, is a signaling adapter molecule involved in p75NTR/NGFR signaling. BEX1 inhibits neuronal differentiation in response to nerve growth factor. BEX1 links between the cell cycle and neurotrophic factor signaling by acting as an upstream modulator of receptor signaling, adjusting biological responses to external signals with internal cellular states.
Description BEX1 Human Recombinant expressed in E. coli is a single polypeptide chain containing 148a.a. (1-125) and having a molecular weight of 17.2kDa. BEX1 is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSMESKEKR AVNSLSMENA NQENEEKEQV ANKGEPLALP LDAGEYCVPR GNRRRFRVRQ PILQYRWDMM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP.
Purity >80% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The BEX1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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