Recombinant Human B3GALTL Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0297
Recombinant Human B3GALTL Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0297
Catalog No.: BLPSN-0297
Product Overview
| Tag | His |
| Host Species | Human |
| Synonym | B3GALTL, B3GTL |
| Background | B3GALTL is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. B3GALTL is a type II membrane protein. Defects in B3GALTL gene are a cause of Peters-plus syndrome (PPS). As an O-fucosyltransferase, B3GALTL transfers glucose toward fucose with a beta-1,3 linkage. It specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. |
| Description | A DNA sequence encoding the human B3GALTL (Ser29-Phe494) was expressed with an N-terminal His tag. |
| Source | HEK293 |
| Predicted N Terminal | His |
| AA Sequence | Ser29-Phe494 |
| Molecular Weight | The recombinant human B3GALTL comprises 486 a.a. and has a predicted molecular mass of 55.4 kDa. The apparent molecular mass of the protein is approximately 54 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
