Name: Recombinant Human ATP1B1 Protein (His Tag)
Brand: Beta LifeScience
SKU: BLPSN-0288
Availability: InStock

Recombinant Human ATP1B1 Protein (His Tag)

Catalog No.: BLPSN-0288

Product Overview

Tag	His
Host Species	Human
Accession	P05026
Synonym	ATP1B
Background	ATP1B1 belongs to the family of Na+/K+ and H+/K+-ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B1 is a subunit of Na+/K+-ATPase. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. Na+/K+-ATPase is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). ATP1B1 regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. ATP1B1 is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane.
Description	A DNA sequence encoding the human ATP1B1 (P05026-1) (Glu63-Ser303) was expressed with an N-terminal His tag.
Source	HEK293
Predicted N Terminal	His
AA Sequence	Glu63-Ser303
Molecular Weight	The recombinant human ATP1B1 comprises 261 a.a. and has a predicted molecular mass of 30.4 kDa. The apparent molecular mass of the protein is approximately 40-47 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Purity	>95% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity	Please contact us for detailed information
Formulation	Lyophilized from sterile PBS, pH 7.4..
Stability	The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.