Recombinant Human ATOX1 Protein
Beta LifeScience
SKU/CAT #: BL-3654PS
Recombinant Human ATOX1 Protein
Beta LifeScience
SKU/CAT #: BL-3654PS
Catalog No.: BL-3654PS
Product Overview
| Tag | His |
| Host Species | Human |
| Synonym | Antioxidant protein 1, ATX1, HAH1, Copper transport protein ATOX1, Metal transport protein ATX1, ATOX1, MGC138453, MGC138455. |
| Background | ATOX1 is a metal transport protein that is part of the ATX1 family. ATOX1 is a copper chaperone that takes part in cellular antioxidant defense and can bind and deliver cytosolic copper to the copper ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. ATOX1 plays a role as an antioxidant against superoxide and hydrogen peroxide, and consequently, takes an important part in cancer carcinogenesis. Because of ATOX1 cytogenetic location, the gene can be a good a candidate gene for 5q-syndrome. |
| Description | ATOX1 Human Recombinant expressed in E.Coli is a single, non-glycosylated, polypeptide chain containing 88a.a. (1-68 a.a.) and having a molecular weight of 9.5kDa. ATOX1 is fused to a 20a.a. His Tag at N-terminus and purified by unique purification methods. |
| Source | E.coli |
| AA Sequence | MGSSHHHHHH SSGLVPRGSH MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK TVSYLGLE. |
| Purity | >95% as determined by SDS-PAGE. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Formulation | ATOX1 solution containing 20mM Tris pH-8, 1mM DTT and 10% glycerol. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze thaw cycles. |
