Recombinant Human ASAM Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0275
Recombinant Human ASAM Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0275
Catalog No.: BLPSN-0275
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NP_079045.1 |
| Synonym | ACAM, ASAM, CSBM, CSBS |
| Background | Adipocyte-specific adhesion molecule (ASAM), also known as ACAM and CLMP, is a type I transmembrane protein and a member of the CTX (cortical thymocyte marker in Xenopus) family within the immunoglobulin superfamily. ASAM protein is highly expressed in the small intestine and placenta, and is found at intermediate levels in the heart, skeletal muscle, colon, spleen, kidney, and lung, and appears in low levels in the liver and peripheral blood leukocytes as well. ASAM is a transmembrane component of tight junctions in epithelial cells that can mediate cell aggregation and regulate transepithelial resistance across polarized epithelial cells. In addition, its expression is strongly correlated with white adipose tissue (WAT) mass of human and rodents with obesity. |
| Description | A DNA sequence encoding the extracellular domain of human ASAM (NP_079045.1) precursor (Met 1-Met 233) was expressed with a C-terminal His tag. |
| Source | HEK293 |
| Predicted N Terminal | Gly 18 |
| AA Sequence | Met 1-Met 233 |
| Molecular Weight | The secreted recombinant human ASAM comprises 227 a.a. and predicts a molecular mass of 25.8 kDa. It migrates as an approximately 32-35 kDa band in SDS-PAGE under reducing conditions. |
| Purity | >97% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
