Name: Recombinant Human AP2 gamma / AP2G Protein (His Tag)
Brand: Beta LifeScience
SKU: BLPSN-0229
Availability: InStock

Recombinant Human AP2 gamma / AP2G Protein (His Tag)

Catalog No.: BLPSN-0229

Product Overview

Tag	His
Host Species	Human
Accession	Q92754
Synonym	AP2-GAMMA, ERF1, hAP-2g, TFAP2G
Background	TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2C may be prognostic indicators for patients with breast tumors. TFAP2C gene has been tested for association to diseases (Breast Neoplasms; Carcinoma) and proposed to participate in processes (cell-cell signaling, male gonad development, regulation of transcription from RNA polymerase II promoter). Proteins are expected to have molecular functions (DNA binding, protein binding, protein dimerization activity, transcription factor activity) and to localize in various compartments (membrane, nucleus).
Description	A DNA sequence encoding the mature form of human TFAP2C (Q92754) (Leu128-Val223) was expressed with a His tag at the N-terminus.
Source	E.coli
Predicted N Terminal	His
AA Sequence	Leu128-Val223
Molecular Weight	The recombinant human TFAP2C consists of 111 a.a. and predicts a molecular mass of 12.3 KDa. It migrates as an approximately 12-14 KDa band in SDS-PAGE under reducing conditions.
Purity	>98% as determined by SDS-PAGE
Endotoxin	Please contact us for more information.
Bioactivity	Please contact us for detailed information
Formulation	Lyophilized from sterile PBS, pH 7.4.
Stability	The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.