Recombinant Human AP2 gamma / AP2G Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0229

Recombinant Human AP2 gamma / AP2G Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0229
Catalog No.: BLPSN-0229
Product Overview
Tag | His |
Host Species | Human |
Accession | Q92754 |
Synonym | AP2-GAMMA, ERF1, hAP-2g, TFAP2G |
Background | TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2C may be prognostic indicators for patients with breast tumors. TFAP2C gene has been tested for association to diseases (Breast Neoplasms; Carcinoma) and proposed to participate in processes (cell-cell signaling, male gonad development, regulation of transcription from RNA polymerase II promoter). Proteins are expected to have molecular functions (DNA binding, protein binding, protein dimerization activity, transcription factor activity) and to localize in various compartments (membrane, nucleus). |
Description | A DNA sequence encoding the mature form of human TFAP2C (Q92754) (Leu128-Val223) was expressed with a His tag at the N-terminus. |
Source | E.coli |
Predicted N Terminal | His |
AA Sequence | Leu128-Val223 |
Molecular Weight | The recombinant human TFAP2C consists of 111 a.a. and predicts a molecular mass of 12.3 KDa. It migrates as an approximately 12-14 KDa band in SDS-PAGE under reducing conditions. |
Purity | >98% as determined by SDS-PAGE |
Endotoxin | Please contact us for more information. |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |