Recombinant Human ABO Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0033
Recombinant Human ABO Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0033
Catalog No.: BLPSN-0033
Product Overview
| Tag | Fc |
| Host Species | Human |
| Accession | ADX99264.1 |
| Synonym | A3GALNT, A3GALT1, GTB, NAGAT |
| Background | ABO (ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase) is a Protein Coding gene. Homologous glycosyltransferases alpha-(1-†’3)-N-acetylgalactosaminyltransferase (GTA) and alpha-(1-†’3)-galactosyltransferase (GTB) catalyze the final step in ABO(H) blood group A and B antigen synthesis through sugar transfer from activated donor to the H antigen acceptor. These enzymes have a GT-A fold type with characteristic mobile polypeptide loops that cover the active site upon substrate binding. The homologous glycosyltransferases alpha-1,3-N-acetylgalactosaminyltransferase (GTA) and alpha-1,3-galactosyltransferase (GTB) carry out the final synthetic step of the closely related human ABO(H) blood group A and B antigens. |
| Description | A DNA sequence encoding the human ABO (ADX99264.1) (Arg63-Pro354) was expressed with the Fc region of human IgG1 at the N-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Glu |
| AA Sequence | Arg63-Pro354 |
| Molecular Weight | The recombinant human ABO consists 552 a.a. and predicts a molecular mass of 62.4 kDa. |
| Purity | >(73.8+20.7)% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
