Recombinant Human G-CSFR Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-2292NP
Recombinant Human G-CSFR Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-2292NP
Product Overview
| Tag | Fc |
| Host Species | Human |
| Accession | Q99062 |
| Synonym | CD114 antigen; CD114; colony stimulating factor 3 receptor (granulocyte); CSF3R; Csfgr; G-CSF R; G-CSF receptor; GCSFR; G-CSFR; GCSFRG-CSF-R |
| Background | Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, the protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis. |
| Description | Recombinant Human Granulocyte Colony-stimulating Factor Receptor is produced by our Mammalian expression system and the target gene encoding Glu25-His627 is expressed with a Fc tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Glu25-His627 |
| Purity | >95% as determined by reducing SDS-PAGE. |
| Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Bioactivity | Contact us for detailed information |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Stability | Recombinant Human G-CSFR protein is stable for 1 year at -70°C |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Usage | For Research Use Only |
| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
